India’s COVID-19 Situation: Mild Uptick with JN.1 Variant in Focus :
India is witnessing a slight increase in COVID-19 cases, primarily driven by the JN.1 variant and its subvariants, LF.7 and NB.1.8, both descendants of the Omicron BA.2.86 lineage. As of May 19, 2025, the Ministry of Health and Family Welfare reported 257 active cases nationwide, with 164 new cases recorded between May 12 and May 19. While the numbers remain low compared to India’s population, health authorities are maintaining vigilance due to surges in other Asian countries like Singapore and Hong Kong.
NEW DELHI – May 23, 2025 – India is currently experiencing a mild, yet noticeable, increase in COVID-19 cases, primarily attributed to the highly transmissible JN.1 variant and its sub-lineages. While the numbers remain low, mirroring similar trends in other Asian nations like Singapore and Hong Kong, health authorities are urging continued vigilance and preparedness, though emphasizing there is no immediate cause for panic.
As of May 19, 2025, India reported 257 active COVID-19 cases nationwide. This figure, while still very low for the country's vast population, represents an uptick of 164 new cases since May 12, prompting closer monitoring by both central and state health departments.
Key Data Points (as of May 19, 2025):
- Total Active Cases: 257 (as of May 19)
- New Cases (since May 12): 164
- Total Reported Cases (cumulative till 2025): Over 45 million
- Total Recovered Patients: 44,508,622
- Total Deaths: 533,632
- Total Vaccination Doses Administered: Over 2.2 billion
Regional Case Distribution:
The recent rise in cases is more pronounced in certain states. As of May 23, Delhi-NCR reported 27 new cases, with 23 in Delhi and 4 in Ghaziabad. Other states with significant active case counts include:
- Kerala: 95 active cases (as of May 19, with 273 cases reported in May)
- Tamil Nadu: 66 active cases (as of May 19)
- Maharashtra: 56 active cases (as of May 19, with 95 new cases in Mumbai alone in May)
- Uttar Pradesh: 44 active cases
- Gujarat: 28 active cases
- Rajasthan: 22 active cases
- Karnataka: 14 active cases
- Haryana reported 4 new mild cases on May 23, all under home observation.
The Role of the JN.1 Variant:
The current surge is largely driven by Omicron sub-variants, specifically JN.1 and its descendants like LF.7 and NB.1.8. The World Health Organization (WHO) has classified JN.1 as a "variant of interest" due to its enhanced transmissibility and ability to partially evade existing immunity. It possesses an additional mutation in its spike protein compared to its parent lineage, BA.2.86 (Pirola), which may contribute to its easier spread.
Despite its high transmissibility, experts across India reiterate that the JN.1 variant is generally causing mild symptoms, akin to a common cold or seasonal influenza. There is no indication of increased disease severity, hospitalizations, or mortality compared to previous Omicron strains. Most patients are recovering at home without requiring intensive medical intervention.
Despite its high transmissibility, experts across India reiterate that the JN.1 variant is generally causing mild symptoms, akin to a common cold or seasonal influenza. There is no indication of increased disease severity, hospitalizations, or mortality compared to previous Omicron strains. Most patients are recovering at home without requiring intensive medical intervention.
Common Symptoms Associated with JN.1:
Symptoms remain largely similar to other Omicron sub-variants and typical flu, including:
- Fever or chills
- Dry cough
- Sore throat
- Headache
- Fatigue/Exhaustion (some patients report more intense fatigue)
- Runny or blocked nose
- Muscle aches
- Nausea or diarrhea (observed more frequently in some cases)
- Loss of taste or smell (less common with JN.1)
Government Response and Expert Assurance:
- Health authorities, including the Indian Council of Medical Research (ICMR) and the National Centre for Disease Control (NCDC), have affirmed that the COVID-19 situation in India remains "under control." Review meetings have highlighted robust surveillance and response mechanisms.
- The Delhi government, among others, has proactively issued advisories to hospitals, urging them to ensure preparedness in terms of bed availability, oxygen, essential medicines, and vaccines. Hospitals are also mandated to send all positive samples for genome sequencing to facilitate timely detection of new variants.
- Health Minister Pankaj Singh of Delhi emphasized that while the government is fully prepared, "There is no need to panic because the strain is similar to influenza." Dr. Jatin Ahuja, an infectious disease specialist, and Dr. Rommel Tickoo, Director, Internal Medicine, also echoed similar sentiments, stating the strain is not leading to a spike in hospitalizations or severe pneumonia.
Recommendations for the Public:
While the overall risk is low, particularly for vaccinated and healthy individuals, continued adherence to COVID-appropriate behaviors is advised:
- Mask Use: Wear face masks in crowded indoor spaces, especially if symptomatic.
- Hand Hygiene: Practice frequent hand washing or use alcohol-based sanitizers.
- Social Distancing: Maintain physical distance where feasible, particularly if feeling unwell.
- Vaccination & Boosters: Stay updated with COVID-19 vaccinations. Booster doses are highly recommended for vulnerable groups, including the elderly, immunocompromised, and those with comorbidities.
- Isolation: If symptomatic, isolate yourself to prevent further spread and seek medical advice.
- Influenza Vaccination: Consider getting the annual influenza vaccine to avoid co-infections.
Comparison with Southeast Asia :
The surge in India is milder compared to other Asian countries:
- Singapore: Reported 14,200 cases in the week ending May 3, 2025, a 28% increase from the previous week, with LF.7 and NB.1.8 accounting for over two-thirds of cases. Hospitalizations have risen, but severe cases remain low.
- Hong Kong: Recorded 1,042 new infections and 31 deaths in the week ending May 10, 2025, the highest weekly toll in a year, primarily among older adults.
- Thailand: An uptick in cases followed the Songkran festival in April, driven by the XEC variant, another Omicron strain.
The current situation underscores that while the pandemic phase may be over, COVID-19 continues to circulate as an endemic disease. India's strategy focuses on proactive monitoring, timely response, and public awareness to manage these periodic fluctuations effectively.